Not everyone gets them side-effects. Furer V., Eviatar T., Zisman D., Peleg H., Paran D., Levartovsky D., Zisapel M., Elalouf O., Kaufman I., Meidan R., et al. Still having intermittent diplopia. However, four cases in our review had a history of long-term oral contraceptives use, which are known as possible risk factors for AMN [18,49]. I called my doctor and was told to go to the ER. I am also experiencing some vision issues in my left eye right after I got my 1st dose of the Moderna vaccine. participated in the preparation, review, and approval of the manuscript. I was seen at the ER for possible stroke. Were do you live? Five minutes after receiving the 2nd vaccine I noticed my vision was distorted. Thanks. Abstracts of Presentations at the Association of Clinical Scientists 143. Most people fully recover, but in some cases people may be left with weakness, pain, or. Her symptoms occurred 10 days after receiving the second mRNA-1273 COVID-19 vaccine. The platelet count ranged from 7000 to 113,000 platelets per cubic millimeter, and most cases were positive for PF4-heparin antibodies [48]. In a case series study, Mazzatenta et al. Eye. We are not sure if the vaccine has a correlation to your double vision. However, because COVID-19 is a new disease, we are unsure what the future will hold for this very nice gentleman. A day or two later i developed Fewer people should get sick, and more lives can be saved. My neuro-Opthalmogist said something is wrong with your windshield. Kadali et al. Helmchen C., Buttler G.M., Markewitz R., Hummel K., Wiendl H., Boppel T. Acute bilateral optic/chiasm neuritis with longitudinal extensive transverse myelitis in longstanding stable multiple sclerosis following vector-based vaccination against the SARS-CoV-2. The vision only got worse and I was diagnosed with diplopia and ptosis by that Friday as I couldnt even see enough to work anymore. reported two cases of corneal graft rejection after the first dose of BNT162b2 COVID-19 vaccine [14]. What You Can Do Post-Vaccine, and When - The New York Times conducted a multicenter observational study on the immunogenicity and safety of the BNT162b2 vaccine in adult patients with autoimmune inflammatory rheumatic diseases. Slit-lamp and fundus examinations were normal and MRI did not reveal brain or orbital abnormalities. Third Cranial Nerve Palsy Presenting with Unilateral Diplopia and Diplopia may be caused by eye problems, eye surgery, or health conditions such as Graves disease or Parkinson disease. and Y.H.H.) She developed vision loss in her right eye 15 days after the second dose of the mRNA-1273 COVID-19 vaccine. Within 10 min of receiving the Moderna vaccine I had a strange taste in my mouth through the right side of my mouth and nose and experienced blurred vision for two days. They did a blood test for ocular myasthenia gravis which came back negative. But my test of antibodies still increasing. In early August, the patient started to experience double vision. Retinal pathologies may be caused by molecular mimicry and self-antigens. The intensity varies too. The mRNA vaccine can also induce antigen-specific cell-and antibody-mediated hypersensitivity reactions and molecular mimicry due to the close resemblance between the vaccine peptide fragments and uveal self-peptides [23,42]. Epidemiology of Ocular Manifestations in Autoimmune Disease. Characteristics of endothelial corneal transplant rejection following immunisation with SARS-CoV-2 messenger RNA vaccine. I am unaware if any studies have been done relating 6th or 4th nerve palsy to viral load. Severe acute respiratory syndrome-coronavirus-2 spike (S) protein based vaccine candidates: State of the art and future prospects. However, the headache worsened, and new homonymous hemianopia occurred the following day. IgG-ELISA for the PF4-heparin complex antibody was positive. Laboratory investigations revealed thrombocytopenia. . We used the following keywords for searching the databases: ((2019-nCoV OR nCoV-19 OR nCoV-2019 OR SARS-CoV-2 OR SARS-CoV2 OR SARSCoV2 OR SARS2 OR COVID OR coronavirus OR coronavirus disease 2019 OR severe acute respiratory syndrome) vaccine) AND (eye OR ocular OR oculopathy OR oculomotor OR intraocular OR extraocular OR ophthalmic OR vision OR orbit OR cornea OR conjunctiva OR retina OR sclera OR vitreous OR diplopia OR metamorphopsia OR visual OR optic)). Ravichandran S., Natarajan R. Corneal graft rejection after COVID-19 vaccination. A bilateral AZOOR was diagnosed [26]. Stroke after COVID-19 vaccine: Is there an increased risk? All three patients purpuric eyelid lesions were asymptomatic and resolved spontaneously after 1015 days [11]. Douxfils J., Favresse J., Dogne J.M., Lecompte T., Susen S., Cordonnier C., Lebreton A., Gosselin R., Sie P., Pernod G., et al.